AN ANTI-UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR ANTIBODY (ATN-658) BLOCKS PROSTATE CANCER INVASION, MIGRATION, GROWTH, AND EXPERIMENTAL SKELETAL METASTASIS IN VITRO AND IN VIVO

An Anti-Urokinase Plasminogen Activator Receptor Antibody (ATN-658) Blocks Prostate Cancer Invasion, Migration, Growth, and Experimental Skeletal Metastasis In Vitro and In Vivo

Urokinase plasminogen activator receptor (uPAR) is a multidomain protein that plays important roles in the growth, invasion, and metastasis of a number of cancers.In the present study, we examined the effects of administration of a monoclonal anti-uPAR antibody (ATN-658) on prostate cancer progression in vitro and in vivo.We examined the effect of

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Remodeling the Dendritic Spines in the Hindlimb Representation of the Sensory Cortex after Spinal Cord Hemisection in Mice.

Spinal cord injury (SCI) can induce remodeling of multiple levels of the cerebral cortex system especially in the sensory cortex.The aim of this study was to assess, in Piano Stool vivo and bilaterally, the remodeling of dendritic spines in the hindlimb representation of the sensory cortex after spinal cord hemisection.Thy1-YFP transgenic mice were

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